2015

72. “Polycyclic N-Heterocyclic Compounds. Part 85: Synthesis and Evaluation of Anti-platelet Aggregation Activity of 2,4-Disubstituted 5,6-Dihydro[1]benzazepino[5,4-d]pyrimidine and Related Compounds” Kensuke Okuda, Ying-Xue Zhang, Takashi Hirota, and Kenji Sasaki; J. Heterocycl. Chem. 52(3), 888–895 (2015).

71. “Polycyclic N-Heterocyclic Compounds Part 84: Reaction of N-(pyrido[3’,2’:4,5]thieno[3,2-d]pyrimidin-4-yl)amidines or N-(pyrido[2’,3’:4,5]furo[3,2-d]pyrimidin-4-yl)amidines with Hydroxylamine Hydrochloride” Kensuke Okuda, Ryota Ide, Naoto Uramaru, and Takashi Hirota; J. Heterocycl. Chem. 52(3), 880–887 (2015).

70. “Polycyclic N-Heterocyclic Compounds. Part 86: Synthesis and Evaluation of Anti-platelet Aggregation Activity of 2,4-Disubstituted 9-Chloro-5,6-dihydropyrimido[5,4-d]benzazepine and Related Compounds” Kensuke Okuda, Shigeki Takarada, Takashi Hirota, and Kenji Sasaki; J. Heterocycl. Chem. 52(3), 780–792 (2015).

69. “A highly sensitive and quantitative assay of IRE1 activity using the small luciferase NanoLuc: evaluation of ALS-related genetic and pathological factors” Takahiro Hikiji, Junpei Norisada, Yoko Hirata, Kensuke Okuda, Hideko Nagasawa, Yusuke Ishigaki, Gen Sobue, Kazutoshi Kiuchi, and Kentaro Oh-hashi; Biochem. Biophys. Res. Commun. 463(4), 881–887 (2015).

68. “N-oxideの化学を利用した鉄(II)イオン蛍光プローブ分子の開発” 平山祐、丹羽正人、奥田健介、永澤秀子; Chemical Biology, 8, 9–11 (2015).

67. “2-[(Neopentyl glycolato)boryl]phenyl Triflates and Halides for Fluoride Ion-Mediated Generation of Functionalized Benzynes” Takashi Ikawa, Rika Yamamoto, Akira Takagi, Toyohiro Ito, Kazunori Shimizu, Masahiko Goto, Yoshitaka Hamashima, Shuji Akai; Adv. Synth. Catal. 357(10), 2287–2300 (2015).

2014

66. “Polycyclic N-Heterocyclic Compounds. Part 79: Synthesis of 2,4-Disubstituted 6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidines as Potential Antiplatelet Aggregators” Kensuke Okuda, Takashi Hirota, and Kenji Sasaki; J. Heterocycl. Chem. 51(6), 1607–1614 (2014).

65. “Polycyclic N-Heterocyclic Compounds. Part 81: Synthesis and Evaluation of Pentacyclic 1,2,4,5-Tetrahydro[1]benzothieno[2’,3’:6,7]thiepino[4,5-e]imidazo[1,2-c]pyrimidine and Related Compounds as Potential Antiplatelet Aggregators” Kensuke Okuda, Yutaka Itsuji, and Takashi Hirota; J. Heterocycl. Chem. 51(5), 1528–1530 (2014).

64. “A new class of high-contrast Fe(II) selective fluorescent probes based on spirocyclized scaffolds” Masato Niwa, Tasuku Hirayama, Kensuke Okuda, and Hideko Nagasawa; Org. Biomol. Chem. 12(34), 6590–6597 (2014).

63. “Polycyclic N-Heterocyclic Compounds. Part 80: Synthesis and Evaluation of Effects on in vitro Pentosidine Formation of 5,6-Dihydro[1]benzothieno[3′,2′:2,3]thiepino[4,5-d]pyrimidine and Related Compounds” Kensuke Okuda, Yutaka Itsuji, Takashi Hirota, and Kenji Sasaki; J. Heterocycl. Chem. 51(4), 891–898 (2014).

62. “Polycyclic N-Heterocyclic Compounds. Part 82: Synthesis and Evaluation of Antiplatelet Aggregation Activity of 2,4-Disubstituted 5,6-Dihydro[1]benzothiepino[5,4-d]pyrimidine and Related Compounds” Kensuke Okuda, Takashi Hirota, and Kenji Sasaki; J. Heterocycl. Chem. 51(4), 911–920 (2014).

61. “Polycyclic N-Heterocyclic Compounds Part 75: Synthesis of 2,4-disubstituted 5,6-dihydro[1]benzoxepino[5,4-d]pyrimidines and 12-substituted 1,2,4,5-tetrahydro[1]benzoxepino[4,5-e]imidazo[1,2-c]pyrimidines as potential anti-platelet aggregators” Kensuke Okuda, Yuko Yamamoto, Takashi Hirota, and Kenji Sasaki; J. Heterocycl. Chem. 51(4), 972–981 (2014).

60. “Optimization of biguanide derivatives as selective antitumor agents blocking adaptive stress responses in the tumor microenvironment” Kosuke Narise, Kensuke Okuda, Yukihiro Enomoto, Tasuku Hirayama, and Hideko Nagasawa; Drug Des. Dev. Ther. 8, 701–717 (2014).

59. “Polycyclic N-Heterocyclic Compounds 83: Synthesis of 2,4-Disubstituted 5,6-Dihydro[1]benzofuro[3’,2’:2,3]oxepino[4,5-d]pyrimidines and 2,4,5-Trisubstituted 5,6-Dihydro[1]benzofuro[2’,3’:5,6]pyrano[4,3-d]pyrimidines from 4-Chloro-5,6-dihydro[1]benzofuro[3’,2’:2,3]oxepino[4,5-d]pyrimidines” Kensuke Okuda, Jun-ichi Takano, Takashi Hirota, and Kenji Sasaki; J. Heterocycl. Chem. 51(3), 788–793 (2014).

58. “Polycyclic N-Heterocyclic Compounds 76: Synthesis and Anti-platelet Evaluation of 2,4-Disubstituted 5,6-Dihydro[1]benzofuro[3’,2’:2,3]oxepino[4,5-d]pyrimidines” Kensuke Okuda, Jun-ichi Takano, Takashi Hirota, Kenji Sasaki, Yuta Nishina, and Hiroyuki Ishida; J. Heterocycl. Chem. 51(3), 661–668 (2014).

57. “Polycyclic N-Heterocyclic Compounds. Part 78: Synthesis of N-[2-([1,2,4]Oxadiazol-5-yl)cyclohepten-1-yl]formamide Oximes and their Evaluation as Inhibitors of Platelet Aggregation” Kensuke Okuda, Ying-Xue Zhang, Takashi Hirota, and Kenji Sasaki; J. Heterocycl. Chem. 51(2), 518–522 (2014).

56. “Facile One-Pot Synthesis of [1,2,3]Triazolo[1,5-a]Pyridines from 2-Acylpyridines by Copper(II)-Catalyzed Oxidative N–N Bond Formation” Tasuku Hirayama, Satoshi Ueda, Takahiro Okada, Norihiko Tsurue, Kensuke Okuda, and Hideko Nagasawa; Chem. Eur. J. 20(14), 4156–4162 (2014).

55. “低酸素・低栄養環境関連分子を標的とする創薬研究の現状” 奥田健介、平山祐、永澤秀子; 放射線生物研究 49(4), 341–357 (2014).

54. “Synthesis of Fluorinated Aromatic Compounds by One-pot Benzyne Generation and Nucleophilic Fluorination” Takashi Ikawa, Shigeaki Masuda, Tsuyoshi Nishiyama, Akira Takagi, Shuji Akai; Aust. J. Chem. 67(3), 475–480 (2014).

2013

53. “A Highly Selective Turn-on Fluorescent Probe for Detection of Iron(II) to Visualize Labile Iron in Living Cells” Tasuku Hirayama, Kensuke Okuda, and Hideko Nagasawa; Chem. Sci. 4(3), 1250–1256 (2013).

52. “Polycyclic N-Heterocyclic Compounds, Part 77: Synthesis of [1]Benzothieno[3’,2’:2,3]oxepino[4,5-d]pyrimidines and Their Evaluations as AntiPlatelet Aggregation Activity” Kensuke Okuda, Takashi Nikaido, Takashi Hirota, and Kenji Sasaki; Synth. Commun. 43(12), 1619–1625 (2013).

51. “Polycyclic N-Heterocyclic Compounds 73: Synthesis and Evaluation of 5-Substituted 1,2-dihydrofuro[2,3-c]isoquinolines as Inducers of Lipoprotein Lipase mRNA Expression” Kensuke Okuda, Masahiko Yoshida, Takashi Hirota, and Kenji Sasaki; J. Heterocycl. Chem. 50(S1), E9–E11 (2013).

50. “FRET-based imaging of transbilayer movement of pepducin in living cells by novel intracellular bioreductively activatable fluorescent probes” Mieko Tsuji, Satoshi Ueda, Tasuku Hirayama, Kensuke Okuda, Yoshiaki Sakaguchi, Aoi Isono, and Hideko Nagasawa; Org. Biomol. Chem. 11(18), 3030–3037 (2013).

49. “Regiocomplementary Cycloaddition Reactions of Boryl- and Silylbenzynes with 1,3-Dipoles: Selective Synthesis of Benzo-Fused Azole Derivatives” Takashi Ikawa, Akira Takagi, Masahiko Goto, Yuya Aoyama, Yoshinobu Ishikawa, Yuji Itoh, Hiroaki Tokiwa, Shuji Akai; J. Org. Chem. 78(7), 2965–2983 (2013).

48. “Generation of 3-Borylbenzynes, Their Regioselective Diels–Alder Reactions, and Theoretical Analysis” Akira Takagi, Takashi Ikawa, Yurio Kurita, Kozumo Saito, Kenji Azechi, Masahiro Egi, Yuji Itoh, Hiroaki Tokiwa, Yasuyuki Kita, Shuji Akai; Tetrahedron 69(21), 4338–4352 (2013).

47. “ortho-Selective Nucleophilic Addition of Amines to 3-Borylbenzynes: Synthesis of Multisubstituted Anilines by the Triple Role of the Boryl Group” Akira Takagi, Takashi Ikawa, Kozumo Saito, Shigeaki Masuda, Toyohiro Ito, Shuji Akai; Org. Biomol. Chem. 11(46), 8145–8150 (2013).

2012

46. “2-Nitroimidazole-Tricarbocyanine Conjugate as a Near-infrared Fluorescent Probe for in Vivo Imaging of Tumor Hypoxia” Kensuke Okuda, Yasuyuki Okabe, Tetsuya Kadonosono, Takahiro Ueno, Bahaa G. M. Youssif, Shinae Kizaka-Kondoh, and Hideko Nagasawa; Bioconjugate Chem. 23(3), 324–329 (2012).

45. “Polycyclic N-Heterocyclic Compounds 74: Rearrangement Reaction of 5-Amino-1,2-dihydrofuro[2,3-c]isoquinolines with a,w-Dibromoalkanes and Evaluation of Product Bronchodilator Activity” Kensuke Okuda, Masahiko Yoshida, Takashi Hirota, and Kenji Sasaki; Synth. Commun. 42(6), 865–871 (2012).

44. “Development of a Hypoxia-selective Near-infrared Fluorescent Probe for Non-Invasive Tumor Imaging” Bahaa Gamal Mohamed Youssif, Kensuke Okuda, Tetsuya Kadonosono, Ola Ibrahim Abdel Razek Salem, Alaa Arafat Mohamed Hayallah, Mostafa Ahmed Hussein, Shinae Kizaka-Kondoh, and Hideko Nagasawa; Chem. Pharm. Bull. 60(3), 402–407 (2012).

43. “Polycyclic N-Heterocyclic Compounds. Part 69: Synthesis of 5-Amino-1,2-dihydro[1]benzofuro[3,2-d]furo[2,3-b]pyridines and Their Transformations to Related Compounds” Kensuke Okuda, Jun-ichi Takano, Takashi Hirota, and Kenji Sasaki; J. Heterocycl. Chem. 49(2), 281–287 (2012).

42. “Evaluating the usefulness of a novel 10B-carrier conjugated with cyclic RGD peptide in boron neutron capture therapy” Shin-ichiro Masunaga, Sadaaki Kimura, Tomohiro Harada, Kensuke Okuda, Yoshinori Sakurai, Hiroki Tanaka, Minoru Suzuki, Natsuko Kondo, Akira Maruhashi, Hideko Nagasawa, and Koji Ono; World J. Oncol., 3(3), 103–112 (2012).

41. “Polycyclic N-Heterocyclic Compounds, Part 72: Reaction of N-([1]Benzofuro (or Benzothieno)[3,2-d]pyrimidin-4-yl)formamidine and N-(Pyrido[2,3-d]pyrimidin-4-yl)formamidine Derivatives with Hydroxylamine Hydrochloride” Kensuke Okuda, Kiyoko Tsuchie, and Takashi Hirota; J. Heterocycl. Chem. 49(4), 755–762 (2012).

40. “Polycyclic N-Heterocyclic Compounds, Part 71: Synthesis and Bronchodilator Evaluation of 5-Substituted 1,2-Dihydrofuro[3,2-f][1,7]naphthyridines and Related Compounds” Kensuke Okuda, Tetsuo Matsushita, Takashi Hirota, and Kenji Sasaki; J. Heterocycl. Chem. 49(4), 742–747 (2012).

39. “3-(2-Oxo-2,3,4,5-tetrahydrofuran-3-yl)[1]benzofuran-2-carbonitrile” Kensuke Okuda, Takashi Hirota, Yuta Nishina, and Hiroyuki Ishida; Acta Cryst. E 68(9), o2819 (2012).

38. “10′-Chloro-3′,4′-dihydro-2′H-spiro[cycroporpane-1,7′(6′H)-pyrimido[2,1-a]isoquinolin]-6′-one” Kensuke Okuda, Takashi Hirota, Yuta Nishina, and Hiroyuki Ishida; Acta Cryst. E 68(11), o3252 (2012).

2011

37. “Polycyclic N-Heterocyclic Compounds, Part 67: Reaction of 6,7-Substituted N-(Quinazolin-4-yl)amidine Derivatives with Hydroxylamine Hydrochloride: Formation of in Vitro Inhibitors of Pentosidine” Kensuke Okuda, Hideki Muroyama, and Takashi Hirota; J. Heterocycl. Chem. 48(6), 1407–1413 (2011).

36. “Isolation, identification, and biological evaluation of HIF-1-modulating compounds from Brazilian green propolis” Hisanori Hattori, Kensuke Okuda, Tetsuji Murase, Yuki Shigetsura, Kosuke Narise, Gregg L. Semenza, and Hideko Nagasawa; Bioorg. Med. Chem. 19(18), 5392–5401 (2011).

35. “Polycyclic N-Heterocyclic Compounds. Part 66: Synthesis of N-[2-([1,2,4]Oxadiazol-5-yl)cyclopenten-1-yl]formamide Oximes and their Evaluation as Inhibitors of Platelet Aggregation” Kensuke Okuda, Ying-Xue Zhang, Hiromi Ohtomo, Takashi Hirota, and Kenji Sasaki; J. Heterocycl. Chem. 48(3), 715–719 (2011).

34. “Polycyclic N-Heterocyclic Compounds. Part 70: Synthesis of 5-Amino-1,2-dihydrofuro[2,3-b]pyrido[3’,2’:4,5]thieno[3,2-d]pyridines and Related Compounds. Evaluation of Effects on Lipoprotein Lipase mRNA Expression” Kensuke Okuda, Hideyasu Takechi, Takashi Hirota, and Kenji Sasaki; Heterocycles 83(6), 1315–1328 (2011).

33. “Polycyclic N-Heterocyclic Compounds, Part 68: Reactions of 3-(2-bromoethyl)quinazolin-4(3H)-one and 3-(2-bromoethyl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one with primary alkylamines via a Dimroth-type rearrangement” Kensuke Okuda, Hiromi Ohtomo, Tsuyoshi Tagata, Takashi Hirota, and Kenji Sasaki; Synth. Commun. 41(6), 812–819 (2011).

32. “Synthesis and evaluation of cyclic RGD-boron cluster conjugates to develop tumor-selective boron carriers for boron neutron capture therapy” Sadaaki Kimura, Shin-ichiro Masunaga, Tomohiro Harada, Yasuo Kawamura, Satoshi Ueda, Kensuke Okuda, and Hideko Nagasawa; Bioorg. Med. Chem. 19(5), 1721–1728 (2011).

31. “A Domino Process for Benzyne Preparation: Dual Activation of o-(Trimethylsilyl)phenols by Nonafluorobutanesulfonyl Fluoride” Takashi Ikawa, Tsuyoshi Nishiyama, Toshifumi Nosaki, Akira Takagi, Shuji Akai; Org. Lett. 13(7), 1730–1733 (2011).

30. “ortho-Selective Nucleophilic Addition of Primary Amines to Silylbenzynes: Synthesis of 2-Silylanilines“ Takashi Ikawa, Tsuyoshi Nishiyama, Takashi Shigeta, Shinya Mohri, Shinsuke Morita, Sho-ichi Takayanagi, Yuki Terauchi, Yuki Morikawa, Akira Takagi, Yoshinobu Ishikawa, Satoshi Fujii, Yasuyuki Kita, Shuji Akai; Angew. Chem. Int. Ed.50(25), 5674–5677 (2011).

2010

29. “7-Chloro-1,2-dihydrofuro[2,3-c]isoquinolin-5-amine” Kensuke Okuda, Takashi Hirota, Kenji Sasaki, and Hiroyuki Ishida; Acta Cryst. E 66(11), o2949 (2010).

28. “Polycyclic N-Heterocyclic Compounds. Part 65: Ring Cleavage Reactions of Fused Furo[2,3-c]isoquinolines and Related Compounds with Various Nucleophiles” Kensuke Okuda, Hiroshi Deguchi, Takashi Hirota, and Kenji Sasaki; Chem. Pharm. Bull. 58(5), 755–757 (2010).

27. “Polycyclic N-Heterocyclic Compounds. Part 64: Synthesis of 5-Amino-1,2,6,7-tetrahydrobenzo[f]furo[2,3-c]isoquinolines and Related Compounds. Evaluation of Their Bronchodilator Activity and Effects on Lipoprotein Lipase mRNA Expression” Kensuke Okuda, Hiroshi Deguchi, Setsuo Kashino, Takashi Hirota, and Kenji Sasaki; Chem. Pharm. Bull. 58(5), 685–689 (2010).

26. “Polycyclic N-Heterocyclic Compounds. Part 63: Improved Synthesis of 5-Amino-1,2-dihydrofuro[2,3-c]isoquinolines via Truce-Smiles Rearrangement and Subsequent Formation to Furo[2,3-c]isoquinoline” Kensuke Okuda, Masahiko Yoshida, Takashi Hirota, and Kenji Sasaki; Chem. Pharm. Bull. 58(3), 363–368 (2010).

25. “Polycyclic N-Heterocyclic Compounds. Part 62: Reaction of N-(Quinazolin-4-yl)amidine Derivatives with Hydroxylamine Hydrochloride and Anti-Platelet Aggregation Activity of the Products” Kensuke Okuda, Ying-Xue Zhang, Hiromi Ohtomo, Takashi Hirota, and Kenji Sasaki; Chem. Pharm. Bull. 58(3), 369–374 (2010).

24. “Polycyclic N-heterocyclic Compounds. Part 61: A Novel Truce-Smiles Type Rearrangement Reaction of 4-(2-Cyanovinyloxy)butanenitriles to Give Cycloalkeno[1,2-d]furo[2,3-b]pyridines” Kensuke Okuda, Norimasa Watanabe, Takashi Hirota, and Kenji Sasaki; Tetrahedron Lett. 51(6), 903–906 (2010).

23. “Preparation and Regioselective Diels-Alder Reactions of borylbenzynes: Synthesis of Functionalized Arylboronates” Takashi Ikawa, Akira Takagi, Yurio Kurita, Kozumo Saito, Kenji Azechi, Masahiro Egi, Keisuke Kakiguchi, Yasuyuki Kita, Shuji Akai; Angew. Chem. Int. Ed. 49(32), 5563–5566 (2010).

2009

22. “Polycyclic N-Heterocyclic Compounds. Part 60: Reactions of 3-(2-Cyanophenyl)quinazolin-4(3H)-ones with Primary Amines” Kensuke Okuda, Tsuyoshi Tagata, Setsuo Kashino, Takashi Hirota, and Kenji Sasaki; Chem. Pharm. Bull. 57(11), 1296–1299 (2009).

21. “Polycyclic N-Heterocyclic Compounds. Part 59: Rearrangement Reactions of Fused Tricyclic 3-(2-Bromoethyl)pyrimidin-4(3H)-ones with Primary Amines via a Dimroth-type Rearrangement” Kensuke Okuda, Hiromi Ohtomo, Fumiaki Tanaka, Takashi Hirota, and Kenji Sasaki; Chem. Pharm. Bull. 57(7), 755–758 (2009).

20. “Synthesis of a Fluorine-Substituted Puromycin Derivative for Brønsted Studies of Ribosomal-Catalyzed Peptide Bond Formation” Kensuke Okuda, Takashi Hirota, David A. Kingery, and Hideko Nagasawa; J. Org. Chem. 74(6), 2609–2612 (2009).

2008

19. “An Uncharged Amine in the Transition State of the Ribosomal Peptidyl Transfer Reaction” David A. Kingery, Emmanuel Pfund, Rebecca M. Voorhees, Kensuke Okuda, Ingo Wohlgemuth, David E. Kitchen, Marina V. Rodnina, and Scott A. Strobel; Chem. Biol. 15(5), 493–500 (2008).

2007

18. Polycyclic N-heterocyclic Compounds. Part 58: Rearrangement Reactions of Fused 3-(2-Bromoethyl)pyrimidin-4(3H)-ones with Primary Amines and Antidepressive Evaluation of the Products” Hiromi Ohtomo, Tsuyoshi Tagata, Kenji Sasaki, Takashi Hirota, and Kensuke Okuda; Tetrahedron 63(51), 12541–12546 (2007).

17. “N-[(Z)-2-(3-Methyl[1,2,4]oxadiazol-5-yl)-2-(1-naphthyl)ethenyl]formamide oxime 1,4-dioxane hemisolvate” Kensuke Okuda, Hiromi Watanabe, Takashi Hirota, Kazuma Gotoh, and Hiroyuki Ishida; Acta Cryst. E 63(11), o4261–o4262 (2007).

16. “N-[5-(1-(Naphthyl)pyrimidin-4-yl)acetamide oxime” Kensuke Okuda, Hiromi Watanabe, Takashi Hirota, and Hiroyuki Ishida; Acta Cryst. E 63(1), o195–o196 (2007).

2005

15. “Uncovering the Enzymatic pKa of the Ribosomal Peptidyl Transferase Reaction Utilizing a Fluorinated Puromycin Derivative” Kensuke Okuda, Amy C. Seila, and Scott A. Strobel; Biochemistry 44(17), 6675–6684 (2005).

14. “Kinetic Isotope Effect Analysis of the Ribosomal Peptidyl Transferase Reaction” Amy C. Seila, Kensuke Okuda, Sara Núñez, Andrew F. Seila, and Scott A. Strobel; Biochemistry 44(10), 4018–4027 (2005).

13. “Human immunodeficiency virus-reverse transcriptase inhibition and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of fullerene derivatives” Tadahiko Mashino, Kumiko Shimotohno, Noriko Ikegami, Dai Nishikawa, Kensuke Okuda, Kyoko Takahashi, Shigeo Nakamura, and Masataka Mochizuki; Bioorg. Med. Chem. Lett. 15(4), 1107–1109 (2005).

2004

12. “Synthesis of isotopically labeled puromycin derivatives for kinetic isotope effect analysis of ribosome catalyzed peptide bond formation” Kensuke Okuda, Amy C. Seila, and Scott A. Strobel; Tetrahedron 60(52), 12101–12112 (2004).

2003

11. “Respiratory Chain Inhibition by Fullerene Derivatives: Hydrogen Peroxide Production Caused by Fullerene Derivatives and a Respiratory Chain System” Tadahiko Mashino, Noriko Usui, Kensuke Okuda, Takashi Hirota, and Masataka Mochizuki; Bioorg. Med. Chem. 11(7), 1433–1438 (2003).

2002

10. “Synthesis of water-soluble C60-porphyrin hybrid compounds” Kensuke Okuda, Chiho Abeta, Takashi Hirota, Masataka Mochizuki, and Tadahiko Mashino; Chem. Pharm. Bull. 50(7), 985–987 (2002).

9. “Effect of Hexasulfobutylated C60 on the Isolated Aortic Ring of Guinea Pig” Shiang Suo Huang, Tadahiko Mashino, Masataka Mochizuki, Long Y. Chiang, Lan Hui Chih, Hung Ming Hsieh, Chen Ming Teng, Kensuke Okuda, Takasi Hirota, Ming Cheng Tsai; Pharmacology 64(2), 91–97 (2002).

2001

8. “Polycyclic N-Heterocyclic Compounds. 56 Reaction of N-(5,6-Dihydro[1]benzoxepino[5,4-d]pyrimidin-4-yl)amidine or Its Amide Oxime Derivatives with Hydroxylamine Hydrochloride” Kenji Sasaki, Ying-Xue Zhang, Kensuke Okuda, and Takashi Hirota; J. Heterocycl. Chem. 38(2), 425–429 (2001).

7. “Inhibitory Effect of Fullerene Derivatives on Glutathione Reductase” Tadahiko Mashino, Kensuke Okuda, Takashi Hirota, Masaaki Hirobe, Tetsuo Nagano, and Masataka Mochizuki; Fullerene Sci. Technol., 9(2), 191–196 (2001).

6. “Polycyclic N-Heterocyclic Compounds. 57 Syntheses of Fused Furo(or Thieno) [2,3-b]pyridine Derivatives via Smiles Rearrangement and Cyclization” Takashi Hirota, Kei-ichiroh Tomita, Kenji Sasaki, Kensuke Okuda, Masahiko Yoshida, and Setsuo Kashino; Heterocycles 55(4), 741–752 (2001).

5. “Effects of hexasulfobutylated C60 on the gastric circular muscle of guinea pig” Shiang Suo Huang, Lan Hui Chih, Chia Hsien Lin, Long Y. Chiang, Tadahiko Mashino, Masataka Mochizuki, Kensuke Okuda, Takasi Hirota, Ming Cheng Tsai; Fullerene Sci. Technol. 9(3), 375–395 (2001).

2000

4. “Synthesis of Various Water-Soluble C60 Derivatives and Their Superoxide-Quenching Activity” Kensuke Okuda, Takashi Hirota, Masaaki Hirobe, Tetsuo Nagano, Masataka Mochizuki, and Tadahiko Mashino; Fullerene Sci. Technol. 8(1&2), 89–104 (2000).

1999

3. “Inhibition of E. coli Growth by Fullerene Derivatives and Inhibition Mechanism” Tadahiko Mashino, Kensuke Okuda, Takashi Hirota, Masaaki Hirobe, Tetsuo Nagano, and Masataka Mochizuki; Bioorg. Med. Chem. Lett. 9(20), 2959–2962 (1999).

1997

2. “Singlet Oxygen Production from Fullerene Derivatives: Effect of Sequential Functionalization of the Fullerene Core”Takeshi Hamano, Kensuke Okuda, Tadahiko Mashino, Masaaki Hirobe, Kumi Arakane, Akemi Ryu, Shinrou Mashiko, and Tetsuo Nagano; Chem. Commun. (1), 21–22 (1997).

1996

1. “Superoxide Radical Quenching and Cytochrome c Peroxidase-like Activity of C60-Dimalonic Acid, C62(COOH)4” Kensuke Okuda, Tadahiko Mashino, and Masaaki Hirobe; Bioorg. Med. Chem. Lett. 6(5), 539–542 (1996).